alzheimers-dementia

First-of-its-kind test can predict dementia up to nine years before diagnosis
June 6, 2024
Researchers have developed a new method for predicting dementia with over 80% accuracy and up to nine years before a diagnosis. The new method provides a more accurate way to predict dementia than memory tests or measurements of brain shrinkage, two commonly used methods for diagnosing dementia....
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Vigorous exercise may preserve cognition in high-risk patients with hypertension
June 6, 2024
People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study suggests that engaging in vigorous physical activity more than once a week can lower that risk.
How stress knocks out your cognitive reserve
June 4, 2024
While mentally stimulating activities and life experiences can improve cognition in memory clinic patients, stress undermines this beneficial relationship.
Astrocytes induce sex-specific effects on memory
May 30, 2024
Scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models. The findings point to astrocytes, brain cells that support and regulate neurons, as key contributors to sex-specific brain mechanisms....
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Study examines prescribing patterns of drug associated with cognitive impairment
May 30, 2024
A new study is one of the first explorations of prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy at healthcare facilities predominantly serving diverse populations of low socioeconomic status. The current body of evidence, much of it established and c...
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Blood flow makes waves across the surface of the mouse brain
May 29, 2024
Researchers have, for the first time, visualized the full network of blood vessels across the cortex of awake mice, finding that blood vessels rhythmically expand and contract leading to 'waves' washing across the surface of the brain. These findings improve the understanding of how the brain receiv...
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First hints of memory problems associated with changes in the brain
May 29, 2024
People who report early memory problems and whose partners also suspect they have memory problems have higher levels of tau tangles in the brain, a biomarker associated with Alzheimer's disease.
Intervention reduces stress and feelings of burden of family caregivers of older adults with dementia
May 29, 2024
Interprofessional research study found that family caregivers of older adults living with dementia experienced a 15% drop in stress after a 9-week online peer support program.
Altering cellular interactions around amyloid plaques may offer novel Alzheimer's treatment strategies
May 27, 2024
Researchers made a significant breakthrough in Alzheimer's disease research by identifying a novel way to potentially slow down or even halt disease progression. The study, which focuses on the role of reactive astrocytes and the plexin-B1 protein in Alzheimer's pathophysiology, provides crucial ins...
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Tracking the cellular and genetic roots of neuropsychiatric disease
May 23, 2024
A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.