Alzheimer’s

Journal article reviews century of data showing COVID-19 likely to impact the brain

Decades of data paint a compelling case for why COVID-19 survivors, even those with few symptoms, could experience long-term effects on the brain and central nervous system.

Solo seniors with cognitive impairment hit hard by pandemic

The pandemic has exacerbated isolation and fears for one very vulnerable group of Americans: the 4.3 million older adults with cognitive impairment who live alone.

A prognostic Alzheimer’s disease blood test in the symptom-free stage

Using a blood test, a research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD). The researchers analyzed blood samples from an SCD co...
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Routine eye scans may give clues to cognitive decline in diabetes

As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes. Scientists now have shown that routine eye imaging can identify changes in the retina that may be associated with cognitive disorders in older people with ...
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Scientists discover mutations associated with early onset dementia

Scientists have announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition that ...
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Sex-specific Alzheimer’s treatment could benefit males over females

A new study found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.

Brain stem cells divide over months

Scientists have been able to observe the way stem cells in the adult brains of mice divide over the course of months to create new nerve cells. Their study shows that brain stem cells are active over a long period, and thus provides new insights that will feed into stem cell research....
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Driving force behind cellular ‘protein factories’ identified

Researchers have identified the driving force behind a cellular process linked to neurodegenerative disorders such as Parkinson's and motor neuron disease.

How a very ‘sociable’ protein can hold clues about Alzheimer’s origin

An international team of scientists has found how the ECSIT protein dictates the behavior of proteins linked to the energy activity in mitochondria, which is largely affected in Alzheimer's disease.

Apathy could predict onset of dementia years before other symptoms

Apathy -- a lack of interest or motivation -- could predict the onset of some forms of dementia many years before symptoms start, offering a 'window of opportunity' to treat the disease at an early stage, according to new research.