Schizophrenia

Whole genome sequencing reveals genetic structural secrets of schizophrenia

Most research about the genetics of schizophrenia has sought to understand the role that genes play in the development and heritability of schizophrenia. Many discoveries have been made, but there have been many missing pieces. Now, UNC School of Medicine scientists have conducted the largest-eve...
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How cognitive intelligence is a whole brain phenomenon

An international collaborative study led by researchers from the NUI Galway provides findings on the neural basis of intelligence, otherwise known as general cognitive ability (IQ).
This new research uses an imaging technique called diffusion tensor imaging (DTI) to provide an insight...
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Researchers find key to keep working memory working

Working memory, the ability to hold a thought in mind even through distraction, is the foundation of abstract reasoning and a defining characteristic of the human brain. It is also impaired in disorders such as schizophrenia and Alzheimer's disease.
Now Yale researchers have found a k...
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A new window into psychosis

A recent study in mice led a team of researchers in Japan to believe that psychosis may be caused by problems with specialized nerve cells deep within the brain, as well as a certain kind of learning behavior. The researchers hope this could provide insight into the emergence of delusions in pati...
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Second type of schizophrenia discovered

Penn Medicine researchers are the first to discover two distinct neuroanatomical subtypes of schizophrenia after analyzing the brain scans of over 300 patients. The first type showed lower widespread volumes of gray matter when compare to healthy controls, while the second type had volumes largel...
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Engaging with schizophrenia: Experts argue for new approaches to treatment

A better understanding of the lived experience of people with schizophrenia would enable clinicians to help patients live with their condition, alongside treating symptoms with medication and psychotherapy, say experts at the University of Birmingham.
According to researchers at the U...
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Unraveling mechanisms of ventricular enlargement linked to schizophrenia

Enlarged cerebral ventricles are found in 80% of individuals with schizophrenia, yet the mechanisms that lead to ventricular enlargement are mostly unknown. Scientists at St. Jude Children's Research Hospital have found that two microRNAs play a critical role in a mechanism that results in ventri...
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New clues into the genetic origins of schizophrenia

The first genetic analysis of schizophrenia in an ancestral African population, the South African Xhosa, appears in the Jan. 31 issue of the journal . An international group of scientists conducted the research, including investigators from Columbia University Mailman School of Public Health and ...
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New insight into how cannabidiol takes effect in the brains of people with psychosis

Published in , the research used fMRI scans to examine the brain activity of 13 people with a diagnosis of psychosis under the influence of a single dose of CBD or placebo and 16 controls whilst they were undertaking a memory task. The researchers showed that, during the task, there was a differe...
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Research offers promise for treating schizophrenia

Research by a University of Georgia psychologist shows that targeting one particular symptom of schizophrenia has a positive effect on other symptoms, offering significant promise for treating an aspect of schizophrenia that currently has no pharmaceutical options.
A team led by Grego...
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