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Heart failure induces cardiac and stem cell aging, Mayo Clinic study finds

March 26, 2023
ROCHESTER, Minn. — Senescence is an aspect of aging that involves a biological dysfunction that occurs in response to repetitive stressors. Biological aging is associated with an increase in the incidence of cardiovascular disease, but whether heart failure is itself a senescent process independent of age is less clear. Senescent cells acquire a phenotype — characteristics that are genetically related — that may lead to inflammation and induce senescence in neighboring cells, which also can…

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