Reactivating aging stem cells in the brain

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers have now discovered a mechanism linked to stem cell aging - and how the production of neurons can be reactivated....
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Neurologists identify consistent neuroinflammatory response in ICH patients

Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease. However, up until now, there has been limited information on inflammation in the brain from human patients, especially during the first days after a hemorrh...
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Eating more refined grains increases risk of heart attack, early death

A new study found consuming a high number of refined grains, such as croissants and white bread, is associated with a higher risk of major cardiovascular disease, stroke and early death.

Evidence of protein folding at site of intracellular droplets

Researchers have found that elevated concentrations of proteins within the droplets triggered a folding event, increasing the potential for protein aggregation -- or misfolding -- which has been linked to neurological diseases including Alzheimer's disease and amyotrophic lateral sclerosis (ALS)....
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Discovery of biomarker could help predict Alzheimer’s years before symptoms emerge

A unique brain protein measured in the blood could be used to diagnose Alzheimer's disease decades before symptoms develop, according to new Edith Cowan University (ECU) research.

Light and genetic probes untangle dynamics of brain blood flow

New research on tiny capillaries and cells called pericytes details how blood moves through over 400 miles of total vasculature in the human brain.

Damage to the heart found in more than half of COVID-19 patients discharged from hospital

Around 50 percent of patients who have been hospitalized with severe COVID-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge, according to new findings....
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Protein linked to Alzheimer’s, strokes cleared from brain blood vessels

Amyloid deposits in the brain increase the risk of dementia and strokes. Researchers have identified an antibody that clears amyloid deposits from the brain without raising the risk of brain bleeds.

High-risk gene for neurodevelopmental disorders linked to sleep problems in flies

The mutation of a gene that has been associated with neurodevelopmental disorders like autism spectrum disorder led to marked sleep disturbances in fruit flies, according to a new study. The findings provide further evidence that sleep is linked to early neurodevelopmental processes and could guide ...
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Mimicking a chronic immune response changes the brain

Researchers show that simulating an overactive autoimmune response in mice leads to changes in the hippocampal region of the brain.