Down Syndrome

Down Syndrome-associated gene suppresses age-related corneal clouding
November 6, 2020
Down syndrome and hypercholesterolemia mouse models suggest that the DSCR-1 gene protects against abnormal cornea vascularization and associated blindness by suppressing oxidized LDL cholesterol production and downstream angiogenic signaling during chronic high cholesterol. While the neurological pa...
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Resolving inflammation: Could it prevent memory loss in Down syndrome and Alzheimer's?
March 13, 2020
Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.
The root cause of Alzheimer's disease is unknown. However, its frequency...
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Global Honors Supermodel Amanda Booth with Quincy Jones Exceptional Advocacy Award
November 15, 2019

What happens when a supermodel has a baby with Down Syndrome? Well, she gets him a modeling contract too (obviously)!.

AMANDA BOOTH TRAVELS the world for her career, modeling in fashion editorials and advertising campaigns for com...
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The Salah Foundation Gifts $75,000 Matching Grant Toward Classes at Global’s New Education Center
November 7, 2019

At Global’s 11th annual Be Beautiful Be Yourself Fashion Show, a surprise announcement was made by Noreen Salah Burpee, Executive Director of the Salah Foundation, and delivered by 9News emcees Kim Christiansen...
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Award-Winning Actor Colin Farrell Goes Above & Beyond for Global
November 3, 2019




Ensuring 2019 Global Ambassador Charlotte Fonfara-LaRose has a ball at the red carpet premiere of
This article was published in the award-winning ...
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Understanding Behavioral Challenges
September 19, 2019
An important study in the journal of mental health research in intellectual disabilities shows that children with Down syndrome demonstrate increased behavioral issues compared with their typical peers. Early intervention and a development strategy can help....
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An Out-Of-Sight Connection
September 13, 2019
Last year, the Global Down Syndrome Foundation’s 10th Anniversary Be Beautiful Be Yourself Fashion Show brought together two very different football fans: Denver Broncos Lineback Von Miller and one of his biggest Admirers, sports-loving 14-year-old Daniel Walshe. Th...
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Targeting key gene could help lead to Down syndrome treatment
May 23, 2019
Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.
Using stem cells that can turn into other cells in the brain, re...
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Down Syndrome Research Could Provide Important Insights Into Cancer Treatments
March 8, 2019


People with Down syndrome are highly protected from most solid tumor cancers, and yet they are highly predisposed to certain blood cancers. Studying people with Down syndrome may lead to new cancer treatments that could benefit everyone.
ACCORDING T...
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Sensitive sensor detects Down syndrome DNA with blood test during pregnancy
February 13, 2019
According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. However, traditional non-invasive prenatal tests for the condition are unreliable or carry risks for the mother and fetus. Now, researchers have develope...
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