Down Syndrome

Down Syndrome-associated gene suppresses age-related corneal clouding

Down syndrome and hypercholesterolemia mouse models suggest that the DSCR-1 gene protects against abnormal cornea vascularization and associated blindness by suppressing oxidized LDL cholesterol production and downstream angiogenic signaling during chronic high cholesterol. While the neurological pa...
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Resolving inflammation: Could it prevent memory loss in Down syndrome and Alzheimer's?

Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.
The root cause of Alzheimer's disease is unknown. However, its frequency...
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Global Honors Supermodel Amanda Booth with Quincy Jones Exceptional Advocacy Award

What happens when a supermodel has a baby with Down Syndrome? Well, she gets him a modeling contract too (obviously)!.

AMANDA BOOTH TRAVELS the world for her career, modeling in fashion editorials and advertising campaigns for com...
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The Salah Foundation Gifts $75,000 Matching Grant Toward Classes at Global’s New Education Center

At Global’s 11th annual Be Beautiful Be Yourself Fashion Show, a surprise announcement was made by Noreen Salah Burpee, Executive Director of the Salah Foundation, and delivered by 9News emcees Kim Christiansen...
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Award-Winning Actor Colin Farrell Goes Above & Beyond for Global

Ensuring 2019 Global Ambassador Charlotte Fonfara-LaRose has a ball at the red carpet premiere of
This article was published in the award-winning ...
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Understanding Behavioral Challenges

An important study in the journal of mental health research in intellectual disabilities shows that children with Down syndrome demonstrate increased behavioral issues compared with their typical peers. Early intervention and a development strategy can help....
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An Out-Of-Sight Connection

Last year, the Global Down Syndrome Foundation’s 10th Anniversary Be Beautiful Be Yourself Fashion Show brought together two very different football fans: Denver Broncos Lineback Von Miller and one of his biggest Admirers, sports-loving 14-year-old Daniel Walshe. Th...
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Targeting key gene could help lead to Down syndrome treatment

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.
Using stem cells that can turn into other cells in the brain, re...
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Down Syndrome Research Could Provide Important Insights Into Cancer Treatments

People with Down syndrome are highly protected from most solid tumor cancers, and yet they are highly predisposed to certain blood cancers. Studying people with Down syndrome may lead to new cancer treatments that could benefit everyone.
ACCORDING T...
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Sensitive sensor detects Down syndrome DNA with blood test during pregnancy

According to the Centers for Disease Control and Prevention, Down syndrome is the most common birth defect, occurring once in every 700 births. However, traditional non-invasive prenatal tests for the condition are unreliable or carry risks for the mother and fetus. Now, researchers have develope...
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