Down Syndrome

Down syndrome research should look at the whole cell not just the extra chromosome, scientists say
December 1, 2022
Research on understanding the effect of extra chromosomes for conditions like Down syndrome typically involves examining what genes play a role in the symptoms of these conditions. However, researchers propose a new way of looking at these conditions, suggesting that when an extra chromosome is pres...
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Down syndrome, like Alzheimer's, is a double-prion disorder, study shows
November 17, 2022
The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study shows that these tangles and plaques are driven by the same a...
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Resolving inflammation: Could it prevent memory loss in Down syndrome and Alzheimer's?
March 13, 2020
Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.
The root cause of Alzheimer's disease is unknown. However, its frequency...
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Global Honors Supermodel Amanda Booth with Quincy Jones Exceptional Advocacy Award
November 15, 2019

What happens when a supermodel has a baby with Down Syndrome? Well, she gets him a modeling contract too (obviously)!.

AMANDA BOOTH TRAVELS the world for her career, modeling in fashion editorials and advertising campaigns for com...
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The Salah Foundation Gifts $75,000 Matching Grant Toward Classes at Global’s New Education Center
November 7, 2019

At Global’s 11th annual Be Beautiful Be Yourself Fashion Show, a surprise announcement was made by Noreen Salah Burpee, Executive Director of the Salah Foundation, and delivered by 9News emcees Kim Christiansen...
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Award-Winning Actor Colin Farrell Goes Above & Beyond for Global
November 3, 2019

Ensuring 2019 Global Ambassador Charlotte Fonfara-LaRose has a ball at the red carpet premiere of
This article was published in the award-winning ...
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Understanding Behavioral Challenges
September 19, 2019
An important study in the journal of mental health research in intellectual disabilities shows that children with Down syndrome demonstrate increased behavioral issues compared with their typical peers. Early intervention and a development strategy can help....
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An Out-Of-Sight Connection
September 13, 2019
Last year, the Global Down Syndrome Foundation’s 10th Anniversary Be Beautiful Be Yourself Fashion Show brought together two very different football fans: Denver Broncos Lineback Von Miller and one of his biggest Admirers, sports-loving 14-year-old Daniel Walshe. Th...
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Targeting key gene could help lead to Down syndrome treatment
May 23, 2019
Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.
Using stem cells that can turn into other cells in the brain, re...
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Down Syndrome Research Could Provide Important Insights Into Cancer Treatments
March 8, 2019

People with Down syndrome are highly protected from most solid tumor cancers, and yet they are highly predisposed to certain blood cancers. Studying people with Down syndrome may lead to new cancer treatments that could benefit everyone.
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