alzheimers-disease

Study identifies potential link between oral bacteria and brain abscesses
December 7, 2022
Researchers have examined the records of 87 patients admitted to hospital with brain abscesses, and found that the 52 patients for whom no cause had been found were about three times as likely to have oral bacteria present in their samples.
Small studies of 40Hz sensory stimulation confirm safety, suggest Alzheimer's benefits
December 1, 2022
Researchers report early stage clinical study results of tests with non-invasive 40Hz light and sound treatment.
New approach for protein-misfolding diseases: Quality control of membrane proteins
December 1, 2022
Researchers have identified a new function of a well-known enzyme: the signal peptidase complex is responsible for the quality control of membrane proteins. The discovery of this new function for a key enzyme in cell biology could lead to new therapeutic approaches for Alzheimer's and other protein-...
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Optimal blood tests for development of new therapies of Alzheimer's disease
December 1, 2022
A new study have identified which blood tests are best at detecting Alzheimer's disease during the earliest stages, and also other another blood test that are is optimal for detecting relevant treatment effects. These findings will speed up the development of new therapies that can slow down the dis...
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Deteriorating neurons are source of human brain inflammation in Alzheimer's disease
December 1, 2022
Scientists have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called senescence. These neurons have a loss of functional activity, impaired metabolism, and increased brain inflammation. The researchers also discovered that targeting...
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Down syndrome research should look at the whole cell not just the extra chromosome, scientists say
December 1, 2022
Research on understanding the effect of extra chromosomes for conditions like Down syndrome typically involves examining what genes play a role in the symptoms of these conditions. However, researchers propose a new way of looking at these conditions, suggesting that when an extra chromosome is pres...
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New analysis of cellular 'vehicles' drives a deeper understanding of ALS, Alzheimer's
December 1, 2022
Scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor protein whose malfunction is associated with many disorders.
Big data analysis powers the fight against Alzheimer's
November 30, 2022
New research findings help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.
Researchers identify the role of an Alzheimer's disease risk gene in the brain
November 30, 2022
A new study links a gene concentrated in the brain’s cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer’s disease. The findings may offer a new potential target for therapies for the intractable condition. ...
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Researchers identify a new marker related to the dysfunction of the glymphatic system
November 30, 2022
A new study shows that wasteosomes -- structures that act as containers for brain waste products -- indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism.