Alzheimer’s

New smart drug delivery system may help treatment for neurological disorders
September 17, 2020
A research team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that co...
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Older people with early, asymptomatic Alzheimer’s at risk of falls
September 15, 2020
Older people without cognitive problems who experience a fall may have undetected neurodegeneration in their brains that puts them at high risk of developing Alzheimer's dementia, according to a new study.
Risk gene for Alzheimer’s has early effects on the brain
September 15, 2020
A genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with certain memory tasks. Researchers find are based on studies with magnetic resonance imaging in individuals at the age of about 20 years. The scientists suspect that the observed effects could ...
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Concussion discovery reveals dire, unknown effect of even mild brain injuries
September 10, 2020
Even mild concussions cause severe and long-lasting impairments in the brain's ability to clean itself, and this may seed it for Alzheimer's, dementia and other neurodegenerative problems.
Vitamin B1 deficiency a key factor in the development of alcohol-related dementia
September 9, 2020
A research group has now developed a hypothesis whereby iron deposits in the brain -- resulting from alcohol-induced vitamin B1 deficiency -- can be regarded as key factors in cognitive decline.
Lumpy proteins stiffen blood vessels of the brain
September 9, 2020
Deposits of a protein called 'Medin', which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.
Unlocking the mystery of tau for treatment of neurodegenerative diseases
September 9, 2020
A team of researchers has uncovered crucial molecular details regarding the activity of the 'tau' protein, promising to revolutionize the therapy of tau-induced neurodegenerative diseases.
Older women with type 2 diabetes have different patterns of blood use in their brains
September 8, 2020
A researcher is reporting that the brains of older women with Type 2 diabetes do not use as much oxygenated blood as those who don't have the disease. The research is the first to point to changes in blood use in the brain as the primary reason for diabetes-related deficits in motor function....
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Brain’s immune cells promising cellular target for therapeutics
September 8, 2020
Inspired by the need for new and better therapies for neurodegenerative diseases, researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia, which are emerging as a promising cellular target because of the prominent role th...
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Common class of drugs linked to increased risk of Alzheimer’s disease
September 4, 2020
Researchers report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease....
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