Why memory-forming neurons are vulnerable to Alzheimer’s
July 1, 2020
Scientists have used advanced technology to 'micro-dissect' the first brain cells to perish in Alzheimer's disease. The result is a short list of genes that could represent new drug targets.
Novel pathology could improve diagnosis and treatment of Huntington’s and other diseases
June 30, 2020
Scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease. The article describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington's disease and may be a common marker of these conditions, which have ...
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Older adults share fewer memories as they age
June 29, 2020
Researchers used a smartphone app to 'eavesdrop' on older adult conversations. They found that the older a person is, the less likely they are to share memories of past experiences.
Why some words may be more memorable than others
June 29, 2020
In a recent study of epilepsy patients and healthy volunteers, researchers found that our brains may withdraw some common words, like ''pig,'' ''tank,'' and ''door,'' much more often than others, including ''cat,'' ''street,'' and ''stair.'' By combining memory tests, brain wave recordings, and surv...
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Repeated head impacts associated with later-life depression symptoms, worse cognitive function
June 26, 2020
In the largest study of its kind, an association has been found in living patients exposed to repetitive head impacts and difficulties with cognitive functioning and depression years or decades later.
Designer peptides show potential for blocking viruses, encourage future study
June 26, 2020
Chemically engineered peptides could prove valuable in the battle against some of the most persistent human health challenges. New findings demonstrate how researchers can engineer peptides capable of selectively and specifically binding to polysialic acid (PSA) -- a carbohydrate that is present in ...
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Scientists devise new ‘bar code’ method to identify critical cell types in the brain
June 25, 2020
A discovery could pave the way for future studies aimed at developing solutions to ALS and other vexing neuromuscular diseases.
One-time treatment generates new neurons, eliminates Parkinson’s disease in mice
June 25, 2020
Researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice's Parkinson's disease symptoms disappear....
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Inflammatory bowel disease linked to doubling in dementia risk
June 23, 2020
Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is linked to a more than doubling in the risk of developing dementia, finds new research.
Alzheimer’s: New gene may drive earliest brain changes
June 22, 2020
A newly discovered Alzheimer's gene appears to drive the first appearance of amyloid plaque in the brain, and could lead to new therapies that prevent the disease from developing.
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