Parkinson's Disease: New theory on the disease's origins and spread
April 11, 2024
New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are the likely source.
Newly found genetic variant defends against Alzheimer's disease
April 10, 2024
Neuroscientists have identified a genetic mutation that fends off Alzheimer's disease in people at high risk and could lead to a new way to protect people from the disease.
Cognitive decline may be detected using network analysis, according to Concordia researchers
April 9, 2024
Researchers use network analysis to study whether it can reveal the subtle changes associated with subjective cognitive decline that cannot otherwise be detected through standard test analyses. By running a statistical analysis of data merged from two large Canadian data sets, the researchers were a...
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Tiny brain bubbles carry complete codes
April 8, 2024
Scientists discovered that the biological instructions within these vesicles differed significantly in postmortem brain samples donated from patients suffering from Alzheimer's disease.
Organoids reveal how to protect the brain against dementia and ALS following traumatic injury, according to study
April 4, 2024
A traumatic brain injury (TBI) can quadruple your risk for developing dementia and increase your chances of developing neurodegenerative diseases such as ALS. In a new study scientists use lab-grown human brain structures known as organoids to offer insights into why this is the case and how to miti...
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Researchers uncover a potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease
April 4, 2024
A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain. Scientists have now found potential ways to interrupt this process...
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Immunotherapy for Alzheimer's disease shows promise in mouse study
April 3, 2024
Scientists have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer's disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain....
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Blended antioxidant supplement improves cognition and memory in aged mice
April 2, 2024
Cell damage from oxidative stress is a major underlying cause of age-related cognitive and muscle strength decline. Antioxidants can reduce oxidative stress and prevent age-related health decline. A new study has found that mice administered with a blended antioxidant supplement show significant imp...
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Simulations reveal mechanism behind protein build-up in Parkinson's disease
April 2, 2024
Researchers have used computational models to understand what drives the accumulation of alpha-synuclein protein, a key culprit in the development of Parkinson's disease.
App may pave way to treatments for no. 1 dementia in under-60s
April 1, 2024
A smartphone app could enable greater participation in clinical trials for people with frontotemporal dementia (FTD), a devastating neurological disorder that often manifests in midlife.