Traumatic Brain Injury (TBI)

The night gardeners: Immune cells rewire, repair brain while we sleep
October 21, 2019
Science tells us that a lot of good things happen in our brains while we sleep -- learning and memories are consolidated and waste is removed, among other things. New research shows for the first time that important immune cells called microglia -- which play an important role in reorganizing the...
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Targeting immune cells may be potential therapy for Alzheimer's
October 11, 2019
Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible in brain scans and people start to become forgetful and confused.
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Dealing a therapeutic counterblow to traumatic brain injury
October 4, 2019
A blow to the head or powerful shock wave on the battlefield can cause immediate, significant damage to a person's skull and the tissue beneath it. But the trauma does not stop there. The impact sets off a chemical reaction in the brain that ravages neurons and the networks that supply them with ...
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Researchers identify molecular process that could accelerate recovery from nerve injuries
October 2, 2019
Twenty million Americans suffer from peripheral nerve injuries, which can be caused by traumas such as combat wounds and motorcycle crashes as well as medical disorders including diabetes. These injuries can have a devastating impact on quality of life, resulting in loss of sensation, motor funct...
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Blood-brain barrier damage occurs even with mild head trauma
September 25, 2019
In a new study of adolescent and adult athletes, researchers at Ben-Gurion University of the Negev, Stanford University and Trinity College in Dublin have found evidence of damage to the brain's protective barrier, without a reported concussion.
For the first time, the researchers wer...
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Fast MRIs offer alternative to CT scans for pediatric head injuries
September 18, 2019
Researchers from the University of Colorado School of Medicine have released a study that shows that a new imaging method "fast MRI" is effective in identifying traumatic brain injuries in children, and can avoid exposure to ionizing radiation and anesthesia.
The results of the study,...
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Alzheimer's disease risk gene APOE4 impairs function of brain immune cells
September 16, 2019
A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer's disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. These findings pave the way for new, effective treatment approaches...
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Advanced MRI brain scan may help predict stroke-related dementia
September 12, 2019
An advanced Magnetic Resonance Imaging (MRI) brain scan analysis in patients with stroke-related, small vessel disease helped predict problems with thinking, memory and even dementia, according to new research published in , a journal of the American Stroke Association, a division of the American...
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Gene therapy helps functional recovery after stroke
September 11, 2019
A new gene therapy turns glial cells -- abundant support cells in the brain -- into neurons, repairing damage that results from stroke and significantly improving motor function in mice. A paper describing the new therapy, which uses the NeuroD1 gene, appears online in the journal . Once further ...
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Repetitive impacts key to understanding sports-associated concussions
September 9, 2019
Scientists at Trinity College Dublin today [Monday September 9] announced a significant advance in our understanding of mild head trauma (concussive brain injury) and how it may be managed and treated in the future. It seems that repetitive impacts -- as opposed to single events -- cause the all-...
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