Cognitive function in people with mental illness
January 22, 2020
A study funded by the Veterans Administration and directed by researchers at the University of Miami Miller School of Medicine has shown few differences in the profiles of genes that influence cognition between people with schizophrenia, bipolar disorder and the general population. This surprisin...
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Hyperactive immune system gene causes schizophrenia-like changes in mice
January 14, 2020
Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal by Ashley Comer and Alberto Cruz-Martín of Boston University and col...
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Molecular switch for repairing central nervous system disorders
January 10, 2020
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and al...
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Long-term medication for schizophrenia is safe, study suggests
January 10, 2020
Researchers at Karolinska Institutet in Sweden and their colleagues in Germany, the USA and Finland have studied the safety of very long-term antipsychotic therapy for schizophrenia. According to the study, which is published in the scientific journal , mortality was higher during periods when pa...
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Air pollution in childhood linked to schizophrenia
January 7, 2020
Air pollution affects physical health, and research results now conclude that it also affects our psychological health. The study, which combines genetic data from iPSYCH with air pollution data from the Department of Environmental Science, shows that children who are exposed to a high level of a...
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Impact of methamphetamine use depends on your genes
December 19, 2019
New research led by La Trobe University in Australia has uncovered genetic clues which could explain why some people have more severe side effects from long-term methamphetamine use than others.
The research, published in found that variations in the gene known as BDNF strongly deter...
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Having a psychotic disorder may increase decline of some areas of cognition over adulthood
December 16, 2019
A new study has shown that relative to participants without a psychotic disorder, those diagnosed with a disorder were consistently impaired across all areas of cognitive (memory and thinking) ability measured. The comparison also suggested that declines in some cognitive areas might worsen with ...
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New protein function could be key to treatment of drug addiction and behavioral disorders
December 5, 2019
The reward pathway of the brain causes feelings of happiness but is also involved in behavioral disorders like schizophrenia and addiction. A breakthrough study has now identified the role of a protein called Npas4 in the reward pathway, mediated by the well-known proteins MAPK and CBP, opening d...
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Chronic adversity dampens dopamine production
November 13, 2019
People exposed to a lifetime of psychosocial adversity may have an impaired ability to produce the dopamine levels needed for coping with acutely stressful situations.
These findings, published today in , may help explain why long-term exposure to psychological trauma and abuse increa...
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Could hair analysis diagnose schizophrenia?
October 29, 2019
A novel approach to probing the biological origins of schizophrenia has identified excess production of hydrogen sulfide in the brain as a factor....
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