Schizophrenia

New insights into biological underpinnings of schizophrenia
October 15, 2019
Researchers have implicated 10 new genes in the development of schizophrenia using a method called whole exome sequencing, the analysis of the portion of DNA that codes for proteins. Working with a global consortium of schizophrenia research teams, Tarjinder Singh, PhD, a postdoctoral fellow affi...
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Potential therapy to treat detrimental effects of marijuana
October 15, 2019
As a growing number of U.S. states legalize the medicinal and recreational use of marijuana, an increasing number of American women are using cannabis before becoming pregnant and during early pregnancy often to treat morning sickness, anxiety, and lower back pain. Although emerging evidence indi...
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Core symptom of schizophrenia reversed in adult mice
October 9, 2019
Columbia researchers have restored normal working memory to a mouse model of schizophrenia, eliminating a core symptom of the disorder that, in people, has proven virtually impossible to treat.
Working memory is a fundamental brain process used to retain and recall information on the ...
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The propensity to hear 'voices' in Schizophrenia may be established by infancy
October 2, 2019
Some people suffering from severe mental illness, particularly schizophrenia, hear "voices," known as auditory hallucinations. This symptom, which afflicts more than 80% of patients, is among the most prevalent and distressing symptoms of schizophrenia. Patients "hear voices" speaking to them or ...
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Scientists identify gene as master regulator in schizophrenia
September 11, 2019
Using computational tools to investigate gene transcription networks in large collections of brain tissues, a scientific team has identified a gene that acts as a master regulator of schizophrenia during early human brain development. The findings may lay the groundwork for future treatments for ...
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Dietary supplement may help with schizophrenia
September 9, 2019
A dietary supplement, sarcosine, may help with schizophrenia as part of a holistic approach complementing antipsychotic medication, according to a UCL researcher.
In an editorial published in the , Professor David Curtis (UCL Genetics, Evolution & Environment and QMUL Centre for P...
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Preventing the onset of schizophrenia in mouse model
September 9, 2019
Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse model of schizophrenia, researchers from the Caroni group at the Friedr...
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Study locates brain areas for understanding metaphors in healthy and schizophrenic people
September 7, 2019
Scientists have used MRI scanners to discover the parts of the brain which understand metaphors, in both healthy volunteers and people with schizophrenia. They found that people with schizophrenia employ different brain circuits to overcome initial lack of understanding. The researchers hope this...
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How our brain filters sounds
September 6, 2019
When two identical sounds are repeated quickly, a filter reduces the attention that the brain directs to the second sound it hears. In people with schizophrenia, this ability to reduce the brain's response to identical sounds does not function properly. But the question is: Why? Neuroscientists h...
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The neurobiological mechanisms behind schizophrenia may depend on gender
September 3, 2019
The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to sc...
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